BRPF1B TRIM24-IN-34

CAS No. 1242907-48-7

BRPF1B TRIM24-IN-34 ( —— )

Catalog No. M10983 CAS No. 1242907-48-7

BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BRPF1B TRIM24-IN-34
  • Note
    Research use only, not for human use.
  • Brief Description
    BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively.
  • Description
    BRPF1B TRIM24-IN-34 is a selective BRPF1B/TRIM24 dual inhibitor that binds with KD of 137 and 222 nM, respectively; exhibits good selectivity over other bromodomains; showes no significant cytotoxicity in a panel of cancer cell lines (GI50>10 uM)
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    Bromodomain
  • Recptor
    Bromodomain
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1242907-48-7
  • Formula Weight
    499.54
  • Molecular Formula
    C24H25N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3,4-dimethoxy-N-(6-(4-methoxyphenoxy)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bennett J, et al. J Med Chem. 2016 Feb 25;59(4):1642-7.
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